Nerviano Medical Sciences announces publication of a research paper in “Chemistry – A European Journal”

Thrilled to announce that our latest paper, in collaboration with Prof. Gian Cesare Tron from Università del Piemonte Orientale (UPO), has just been published in the prestigious “Chemistry – A European Journal”! You can check it out here: link. This publication highlights the strong and productive partnership between our two institutions. By building on the […]
Nerviano Medical Sciences will be exhibiting at the SCI-2024 – XXVIII National Congress

Nerviano Medical Sciences will be exhibiting at the SCI-2024 – XXVIII National Congress, the main Chemistry event in Italy. Meet us from August 26th to August 30th at booth #133 Allianz MiCo Congress Center, Milan, Nord Wing- Level +1 Hope to see you there!
We are speaking at the 3rd GLOBAL XDC INNOVATION CONFERENCE in WuXi (CHINA)!

We are speaking at the 3rd GLOBAL XDC INNOVATION CONFERENCE in WuXi (CHINA) partnering event in WuXi (CHINA) , 10 – 12 Sep. 2024 We look forward to your presence to explore future partnership opportunities. * * * * * Contact: Valsasina Barbara : Barbara.Valsasina@demo111.axxiem.com Lupi Rosita: rosita.lupi@demo111.axxiem.com * * * * * About NMS […]
Present Scenario and Future Landscape of Payloads for ADCs: Focus on DNA-Interacting Agents

Valsasina B., Orsini P., Terenghi C., Ocana A. Pharmaceuticals 2024, 17, 1338.
Visible Light Promoted Site-Specific Functionalization of α-Acyloxy Carboxamides: Unlocking a Forbidden Chemical Space in the Passerini Reaction

Brunelli F, Quartieri F, Miletto I, Pulici M, Papeo G, Tron GC Chemistry (2024), 5;30(50), e202402175
Discovery and optimization of 4-pyrazolyl-2-aminopyrimidine derivatives as potent spleen tyrosine kinase (SYK) inhibitors

Cervi G, D’Alessio R, Bindi S, Buffa L, Burocchi A, Canevari G, Modugno M, Motto I, Saturno G, Orsini P Eur J Med Chem (2024), 270, 116375
Photocatalytic radical coupling of organoborates with α-Halogenated electron-poor olefins

Caldarelli M, Rezzi SJ, Colombo N, Pirali T, Papeo G J Org Chem (2024), 5, 89(1), 633-643
A novel platform of diversified cytotoxins and targeted payloads to drive ADC innovation

P. Orsini, M. Salsa, S. Rizzi, U. Cucchi, D. Faiardi, A. Burocchi, A. Ciavolella, R. Lupi, F. Gasparri, B. Valsasina AACR Annual Meeting 2024; April 5-10, 2024; San Diego –Abstract 5805 Cancer Res (2024) 84 (6_Supplement)
The MPS1/TTK inhibitor, NMS-01940153, synergizes with tisotumab vedotin in colorectal cancer

G. Texido, F. Gasparri, A. Ciavolella, L. Gianellini, A. Burocchi, I. Fraietta, A.E. Pedersen, A. Ocaña, R. Colombo, D. Roberti, L. Mahnke, C. Perrera AACR Annual Meeting 2024; April 5-10, 2024; San Diego –Abstract 509 Cancer Res (2024) 84 (6_Supplement)
Development of 14-amino-anthracyclines as novel payloads for ADC production showing potent anti-tumor activity and improved safety profile

P. Orsini, M. Salsa, A. Burocchi, A. Ciavolella, U. Cucchi, D. Faiardi, S. Rizzi, F. Gasparri, B. Valsasina 38th National Medicinal Chemistry Symposium; June 23-26, 2024; Seattle, WA.