25 years of DNA Encoded Chemistry: managing serendipity in pre-clinical small molecule drug discovery?” Barry Morgan

Jun 18, 2019 (11.00 AM) 25 years of DNA Encoded Chemistry: managing serendipity in pre-clinical small molecule drug discovery?” Barry Morgan HitGen Inc., Chengdu, China & University of Texas Health Sciences, Institute for Molecular Medicine, Houston Texas

Comprehensive kinome NGS targeted expression profiling by KING-REX

Carapezza G, Cusi C, Rizzo E, Raddrizzani L, Di Bella S, Somaschini A, Leone A, Lupi R, Mutarelli M, Nigro V, di Bernardo D, Magni P, Isacchi A, Bosotti R BMC Genomics (2019), 20(1), 307

Discovery of Stereospecific PARP-1 Inhibitor Isoindolinone NMS-P515

G. Papeo, P. Orsini, N. Avanzi, D. Borghi, E. Casale, M. Ciomei, A. Cirla, V. Desperati, D. Donati, E. R. Felder, A. Galvani, M. Guanci, A. Isacchi, H. Posteri, S. Rainoldi, Federico Riccardi-Sirtori,§ Alessandra Scolaro,∥and Alessia Montagnoli ACS Medicinal Chemistry Letters 2019

An antibody-drug conjugate directed to the ALK receptor demonstrates efficacy in preclinical models of neuroblastoma

Sano R, Krytska K, Larmour CE, Raman P, Martinez D, Ligon GF, Lillquist JS, Cucchi U, Orsini P, Rizzi S, Pawel BR, Alvarado D, Mossé YP Sci Transl Med (2019), 11(483)

Neutrophil Elastase Promotes Linker Cleavage and Paclitaxel Release from an Integrin-Targeted Conjugate

Raposo Moreira Dias A, Pina A, Dean A, Lerchen HG, Caruso M, Gasparri F, Fraietta I, Troiani S, Arosio D, Belvisi L, Pignataro L, Dal Corso A, Gennari C Chemistry (2019), 25(7), 1696-1700

A benchmarking of pipelines for detecting ncRNAs from RNA-Seq data

Di Bella S, La Ferlita A, Carapezza G, Alaimo S, Isacchi A, Ferro A, Pulvirenti A, Bosotti R Brief Bioinform. 2020 Dec 1;21(6):1987-1998. doi: 10.1093/bib/bbz110. PMID: 31740918

Investigating miRNA-IncRNA interactions: Computational tools and resources

Veneziano D, Marceca GP, Di Bella S, Nigita G, Distefano R, Croce CM Methods Mol Biol (2019), 1970 (Chapt 14), 251-277

Drug-Initiated synthesis of Heterotelechelic Polymer Prodrug Nanoparticles for in vivo imaging and cancer cell targeting

Vinciguerra D, Degrassi A, Mancini L, Mura S, Mougin J, Couvreur P, Nicolas J Biomacromolecules (2019), 20(7), 2464-2476

Mechanism of action of the tumor vessel targeting agent NGR-hTNF: Role of both NGR peptide and hTNF in cell binding and signaling

Valentinis B, Porcellini S, Asperti C, Cota M, Zhou D, Di Matteo P, Garau G, Zucchelli C, Avanzi NR, Rizzardi GP, Degano M, Musco G, Traversari C Int J Mol Sci (2019), 20(18), 4511-4533

16th Annual Meeting of the Bioinformatics Italian Society

June 26-28 Palermo, Italy 16th Annual Meeting of the Bioinformatics Italian Society