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Publications 2006




Analysis of brostallicin effect on different human gastrointestinal cancer cell lines
Scovassi AI, Gorrini C, Pastori W, Ciomei M
Letters in Drug Design & Discovery
(2006) 3, 524-527

C-C- bond forming reactions
Brill WK.-D, Papeo G
Combinatorial Chemistry
(2006) 26,143-360

3-Amino-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazoles: a new class of CDK2 inhibitors
Pevarello P, Fancelli D, Vulpetti A, Amici R, Villa M, Pittalà V, Vianello P, Cameron A, Ciomei M, Mercurio C, Bischoff JR, Roletto F, Varasi M and Brasca MG
Bioorganic and Medicinal Chemistry Letters
(2006) 16, 1084-1090

Compounds and methods for inhibiting mitotic progression
Fancelli D
Expert Opin Ther Patents
(2006) 16(8), 1179-1182


1,4,5,6-Tetrahydropyrrolo [3,4-c]pyrazoles: Identification of a Potent Aurora Kinase Inhibitor with a Favorable Antitumor Kinase Inhibition Profile
Fancelli D, Moll J, Varasi M, Bravo R, Artico R, Berta D, Bindi S, Cameron A, Candiani I, Cappella P, Carpinelli P, Croci W, Forte B, Giorgini ML, Klapwijk J, Marsiglio A, Pesenti E, Rocchetti M, Roletto F, Severino D, Soncini C, Storici P, Tonani R,
J Med Chem
(2006) 49, 7247-7251

Bicyclic Carbohydrate-Derived Scaffolds for Combinatorial Libraries
Cervi G, Peri F, Battistini C, Gennari C, Nicotra
Bioorganic & Medicinal Chemistry
(2006), 14, 3349-3367

Structure-based Drug Design to the Discovery of New 2-aminothiazole CDK2 Inhibitors
Vulpetti A, Casale E, Roletto F, Amici R, Villa M, Pevarello P
Journal of Molecular Graphics and Modelling
(2006) 24, 341-348

Inhibition of Protein-Protein Interactions: The Discovery of Druglike B-Catenin Inhibitors by Combining Virtual and Biophysical Screening
Trosset J, Dalvit C, Knapp S, Fasolini M, Veronesi M, Mantegani S, Gianellini L, Catana C, Sundström M, Stouten P, Moll J
Proteins: Structure, Function and Bioinformatics
(2006) 64, 60-67


1,3,4-Oxadiazole formation as traceless release in solid phase organic synthesis
Cesarini S, Colombo N, Pulici M, Felder ER and Brill WK-D
Tetrahedon Letters
(2006) 62, 10223-10236

Multiparametric cell-cycle analysis by automated microscopy
Gasparri F, Cappella P, Galvani A
J Biomol Screen
(2006) 11(6), 586-598

NMR-Based Quality Control Approach for Identification of False Positives and False Negatives in High Throughput Screening
Dalvit C, Caronni D, Mongelli N, Veronesi M, Vulpetti A
Current Drug Discovery Technologies
(2006) 3, 115-124

PHA-680632, a novel Aurora kinases inhibitor with potent anti-tumoral activity
Soncini C, Carpinelli P, Gianellini L, Fancelli D, Vianello P, Rusconi L, Storici P, Zugnoni P, Pesenti E, Croci V, Ceruti R, Giorgini ML, Cappella P, Ballinari D, Sola F, Varasi M, Bravo R, Moll J
Clinical Cancer Research
(2006) 12(13), 4080-4089

Cyclin-Dependent Kinase 2 function in normal DNA repair and is a therapeutic target in BRCA1- deficient Cancers
Deans AJ, Khanna KK, McNees CJ, Mercurio C, Heierhorst J and McArthur GA
Cancer Research
(2006) 66(16), 8219-8226

A practical synthesis of the major metabolite of a potent CDK2/cyclin A inhibitor
Nesi M, Borghi D, Brasca MG, Fiorentini F and Pevarello P
Bioorganic & Medicinal Chemistry Letters
(2006) 16, 3205-3208

Identification of Mcm2 phosphorylation sites by S-phase regulating kinases
Montagnoli A, Valsasina B, Brotherton D, Troiani S, Rainoldi S, Tenca PL, Molinari A and Santocanale C
The Journal of Biological Chemistry
(2006) 281(5), 10281-10290