Biology Department

Established to effectively address all biochemical and biologically related aspects of the discovery projects, utilizing state-of-the-art molecular oncology approaches from in vitro screening to in vivo efficacy and biomarker identification for clinical development

The Biology Department includes:

Biotechnology

• production and characterization of proteins for HTS and crystallization
• gene expression analysis with microarrays and real-time PCR
• identification of biomarkers
  

Cell Cycle laboratory

• biochemical mechanism of inhibition studies
• target validation
• automated biochemical and cell-based secondary assays
• assessment of mechanism of action and compound activity by using molecular approaches and state-of-the-art technologies

In Vivo Pharmacology

• evaluation of the potential of new cancer therapies utilizing advanced tumor models
• Magnetic Resonance Imaging
• in vivo analysis